Please use this identifier to cite or link to this item: http://ir.swu.ac.th/jspui/handle/123456789/13554
Title: Low-cost and disposable sensors for the simultaneous determination of coenzyme Q10 and α-lipoic acid using manganese (IV) oxide-modified screen-printed graphene electrodes
Authors: Charoenkitamorn K.
Chaiyo S.
Chailapakul O.
Siangproh W.
Keywords: Chemical detection
Coenzymes
Cyclic voltammetry
Dietary supplements
Graphene
Graphite electrodes
Manganese oxide
Coenzyme Q10
Electroactive surface areas
Lipoic acids
Modified electrode surfaces
Quantitative determinations
Screen-printed graphene electrodes
Simultaneous determinations
Square wave anodic stripping voltammetry
Electrochemical electrodes
graphene
manganese oxide
thioctic acid
ubidecarenone
graphite
manganese derivative
manganese oxide
oxide
thioctic acid
ubidecarenone
ubiquinone
accuracy
anodic stripping potentiometry
Article
concentration (parameters)
cost
cyclic potentiometry
dietary supplement
electric capacitance
electrochemistry
enzyme assay
limit of detection
priority journal
quantitative analysis
screen printed graphene electrode
square wave anodic stripping potentiometry
analogs and derivatives
chemical structure
chemistry
electrochemical analysis
electrode
printing
Electrochemical Techniques
Electrodes
Graphite
Manganese Compounds
Molecular Structure
Oxides
Printing
Thioctic Acid
Ubiquinone
Issue Date: 2018
Abstract: In this work, for the first time, manganese (IV) oxide-modified screen-printed graphene electrodes (MnO2/SPGEs) were developed for the simultaneous electrochemical detection of coenzyme Q10 (CoQ10) and α-lipoic acid (ALA). This sensor exhibits attractive benefits such as simplicity, low production costs, and disposability. Cyclic voltammetry (CV) was used to characterize the electrochemical behavior of the analyte and investigate the capacitance and electroactive surface area of the unmodified and modified electrode surfaces. The electrochemical behavior of CoQ10 and ALA on MnO2/SPGEs was also discussed. Additionally, square wave anodic stripping voltammetry (SWASV) was used for the quantitative determination of CoQ10 and ALA. Under optimal conditions, the obtained signals are linear in the concentration range from 2.0 to 75.0 μg mL−1 for CoQ10 and 0.3–25.0 μg mL−1 for ALA. The low limits of detection (LODs) were found to be 0.56 μg mL−1 and 0.088 μg mL−1 for CoQ10 and ALA, respectively. Moreover, we demonstrated the utility and applicability of the MnO2/SPGE sensor through simultaneous measurements of CoQ10 and ALA in dietary supplements. The sensor provides high accuracy measurements, exhibiting its high potential for practical applications. © 2017 Elsevier B.V.
URI: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85039942501&doi=10.1016%2fj.aca.2017.12.026&partnerID=40&md5=36787145d736028042d06dd5674b43e0
http://ir.swu.ac.th/jspui/handle/123456789/13554
ISSN: 32670
Appears in Collections:Scopus 1983-2021

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