Please use this identifier to cite or link to this item: http://ir.swu.ac.th/jspui/handle/123456789/12322
Title: Generation of two human iPSC lines (MDCUi001-A and MDCUi001-B) from dermal fibroblasts of a Thai patient with X-linked osteogenesis imperfecta using integration-free Sendai virus
Authors: Tongkobpetch S.
Rungsiwiwut R.
Pruksananonda K.
Suphapeetiporn K.
Shotelersuk V.
Keywords: afp1 protein
alpha smooth muscle actin
beta tubulin
cell marker
genomic DNA
glyceraldehyde 3 phosphate dehydrogenase
kruppel like factor 4
membrane bound transcription factor peptidase site 2
Myc protein
octamer transcription factor 4
peptidase
rex1 protein
tra 1 60 protein
tra 1 81 protein
transcription factor
transcription factor NANOG
transcription factor Sox2
unclassified drug
kruppel like factor
kruppel like factor 4
Myc protein
MYC protein, human
SOX2 protein, human
transcription factor Sox
Article
cell clone
cell differentiation
cell reprogramming technique
child
controlled study
ectoderm
embryoid body
endoderm
human
human cell
in vitro study
induced pluripotent stem cell
karyotype
male
mdcui001 a cell line
mdcui001 b cell line
mesoderm
nonhuman
nuclear reprogramming
osteogenesis imperfecta
pluripotent stem cell line
point mutation
preschool child
priority journal
Sendai virus
short tandem repeat
skin fibroblast
Thai (people)
cell line
cytology
fibroblast
genetics
induced pluripotent stem cell
metabolism
osteogenesis imperfecta
physiology
Sendai virus
Thailand
Cell Differentiation
Cell Line
Fibroblasts
Humans
Induced Pluripotent Stem Cells
Karyotype
Kruppel-Like Transcription Factors
Male
Osteogenesis Imperfecta
Proto-Oncogene Proteins c-myc
Sendai virus
SOXB1 Transcription Factors
Thailand
Issue Date: 2019
Abstract: Two clones of human induced pluripotent stem cells (iPSCs) were generated from dermal fibroblasts isolated from a one-year-old Thai patient with X-linked osteogenesis imperfecta. The patient harbored a mutation, p.N459S, in the MBTPS2 gene. The cells were reprogrammed using an integration-free Sendai virus containing KLF4, c-MYC, OCT4 and SOX2. Both of the established iPSC lines (MDCUi001-A and MDCUi001-B) maintained normal karyotype, expressed pluripotent markers and differentiated into all three germ layers. © 2019
URI: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85069590379&doi=10.1016%2fj.scr.2019.101493&partnerID=40&md5=4e1ce5eee7a33b41e23cb8f86cf3a22a
http://ir.swu.ac.th/jspui/handle/123456789/12322
ISSN: 18735061
Appears in Collections:SCOPUS 1983-2021

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