Please use this identifier to cite or link to this item: http://ir.swu.ac.th/jspui/handle/123456789/12292
Title: Comparison of Endothelial Keratoplasty Techniques in Patients With Prior Glaucoma Surgery: A Case-Matched Study
Authors: Lin S.R.
Prapaipanich P.
Yu F.
Law S.K.
Caprioli J.
Aldave A.J.
Deng S.X.
Keywords: Article
best corrected visual acuity
case control study
case study
central corneal thickness
clinical outcome
controlled study
Descemet membrane endothelial keratoplasty
Descemet stripping endothelial keratoplasty
endothelial keratoplasty
endothelial rejection
female
follow up
glaucoma
glaucoma surgery
graft failure
human
human cell
human tissue
intermethod comparison
intraocular pressure
major clinical study
male
outcome assessment
postoperative complication
postoperative intraocular pressure elevation
preoperative period
priority journal
retrospective study
surgical technique
trabeculectomy
aged
comparative study
complication
cornea disease
filtering operation
glaucoma
graft rejection
graft survival
incidence
keratometry
procedures
prognosis
reoperation
United States
visual acuity
Aged
Corneal Diseases
Corneal Topography
Descemet Stripping Endothelial Keratoplasty
Female
Filtering Surgery
Follow-Up Studies
Glaucoma
Graft Rejection
Graft Survival
Humans
Incidence
Male
Prognosis
Reoperation
Retrospective Studies
United States
Visual Acuity
Issue Date: 2019
Abstract: Purpose: To compare the outcomes of Descemet membrane endothelial keratoplasty (DMEK) with those of Descemet's stripping endothelial keratoplasty (DSEK) in eyes with prior glaucoma surgery. Design: Case-matched retrospective comparative case series. Methods: Setting/study population: 46 DMEK procedures were matched with 46 DSEK procedures at a single institution. Observation procedures: cases were matched based on preoperative visual acuity, lens status, and surgical indication. Main outcome measurements: the outcome measurements included visual acuity improvement, primary and secondary graft failure, endothelial rejection, intraocular pressure (IOP) elevation, and the need for additional glaucoma intervention. Results: Best-corrected visual acuity (BCVA) improved by −0.89 logMAR in the DMEK group and −0.62 logMAR in the DSEK group (P = 0.005) at 1 year follow-up. Visual acuity was significantly better in the DMEK group at postoperative months 1, 3, and 12 and at last follow-up. The percentage of patients achieving 20/40 or better best-corrected visual acuity was higher in the DMEK group at all time points, notably 47% in the DMEK group versus 15% in the DSEK group at 1 year (P = 0.002). Secondary graft failure was lower in the DMEK group (DMEK 0% vs. DSEK 17%; P = 0.006). Primary graft failure rates and rebubling rates were similar. There were no differences in the rates of postoperative IOP elevation or in the need for additional glaucoma intervention. Conclusions: In complex eyes with prior glaucoma surgery, DMEK offers faster visual recovery, better final visual acuity, and a lower rate of secondary graft failure compared to DSEK during the first postoperative year and beyond. © 2019
URI: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85068884475&doi=10.1016%2fj.ajo.2019.03.020&partnerID=40&md5=669cf05023e9c2540b9a57bd313726f9
http://ir.swu.ac.th/jspui/handle/123456789/12292
ISSN: 29394
Appears in Collections:SCOPUS 1983-2021

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